WHO made the declaration after Liberia reported no new Ebola cases for 42 days, twice the maximum incubation period for the deadly disease.
However, the West African region is still affected by the disease. Sierra Leone and Guinea — Liberia's neighbors — each reported nine cases of the disease last week.
WHO has also announced changes to its post-Ebola guidelines. The agency is urging formerly infected men and their sexual partners to either abstain from sex or practice safe sex for six months, enough time to have two semen tests that are negative for the Ebola virus.
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